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The androgenic effects include, among other things, penile growth, hair in various areas, and baldness while the anabolic affects include, among other things, the enlargement of the larynx, the thickening of the vocal cords, lipid changes, muscle growth, reduced fatty tissue, the enlargement of the sebaceous glands, and formation of blood cells. Androgens have psychological effects on the libido, virility, sexual behaviour, and aggressiveness . Anabolic steroids are synthetic derivatives of testosterone. With these, the field of medicine has sought to obtain the anabolic effect of testosterone without its virilizing adverse effects so that women and children could use anabolic steroids as well. These efforts have failed, however. For this reason, the term ‘anabolic steroid’ is somewhat misleading. As a term, ‘anabolic androgenic steroid’ is more accurate . Testosterone is the body’s natural anabolic androgenic steroid. Testosterone and other anabolic steroids have the same basic chemical structure, buy proviron 25 mg oral steroids $42.00 proviron. There have been efforts to change the structure of synthetic anabolic steroids by increasing the anabolic effect and reducing the androgenic effect . The anabolic-androgenic ratio of testosterone is 1:1 and both effects are strong. In the case of other anabolic steroids, this ratio varies so that the anabolic effect is greater [2, 6]. Furthermore, the anabolic steroid structure has been changed so that, for instance, administration, absorption, duration, and aromatization can be varied. So, the various anabolic steroids differ from one another by their androgenic ratio and administration (oral or intramuscular injection or dermal application), by their absorption time and duration of action, as well as whether they are aromatized into estrogens [7, 8]. The use of modern testosterone can be estimated to have begun in 1935 when testosterone was successfully isolated from bull testicles. Rather quickly, it was discovered that oral testosterone is hepatoxic and that it has a fast half-life. After testosterone was synthesized, injectable propionate entered the markets and, later in the 1950s, the longer acting enanthate. In the 1950s and the 1960s, the pharmaceutical industry grew more and more interested in new androgens and by the end of the 1980s countless’up to more than a thousand’anabolic steroids, had been developed [9, 10]. Testosterone and all anabolic steroids affect the body through the androgen receptors. The androgen receptors are located in the X chromosome of the cells and they are widely found in the body. Androgen receptors affect the muscles, but also the heart, immunity, and the nervous system, among other things . The popularity of testosterone as a doping substance can be explained by its strong effect on muscular strength and mass. Testosterone also affects lipolysis, or the breakdown of fatty cells. Both short-term and long-term use of anabolic steroids lead to pronounced cell growth due to the added protein synthesis. The muscle cell growth induced by testosterone is stems from the activation of satellite cells and the growth of muscle cell nuclei .
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